Kevin, Stuart and Bob, having been accidentally dropped off at the North Pole, make the most of the situation by trying to become elves.

When Van Helsing's mysterious invention, the "Monsterfication Ray", goes haywire, Drac and his monster pals are all transformed into humans, and Johnny becomes a monster. In their new mismatched bodies, Drac, stripped of his powers, and an exuberant Johnny, loving life as a monster, must team up and race across the globe to find a cure before it's too late, and before they drive each other crazy. With help from Mavis and the hilariously human Drac Pack, the heat is on to find a way to switch themselves back before their transformations become permanent.