A curious and lost Eleonore looks for something everywhere, even in the bags of strangers who find themselves sadly smiling only well after she's left their lives. They owe her their thanks.

A father juggling his kids with the rest of his responsibilities is ultimately faced with the choice of being their father or their friend.

Driven by the irrepressible, daily need to have a fix, Harley, a homeless, substance-dependent young woman, thinks that she has found true love in the mean streets of bustling New York City. But then, Ilya, her abusive, drug-addled boyfriend, who dominates her vulnerable heart and gives her a reason to live, asks the unthinkable. Suddenly, devotion becomes a cruel word, and only self-sacrifice can bring atonement. Now, desperate Harley is ready to do Ilya's bidding without a second thought; however, before long, she will have to make a tough decision: choose between her love for Ilya and her unbreakable heroin addiction.

Connie Nikas forcibly removes his developmentally disabled brother Nick from a therapy session. The two rob a New York City bank for $65,000. In the getaway car, a dye pack explodes in a money bag, causing the driver to crash. Connie and Nick flee on foot, washing the dye from their clothes in a restaurant restroom. Stopped by police, Nick panics and runs; Nick is arrested while Connie escapes. Connie attempts to secure a bail bond, but needs $10,000 more to get Nick out of jail. He convinces his girlfriend, Corey, to pay with her mother's credit cards, but her mother cancels the cards. Connie learns that Nick has been hospitalized after a fight with an inmate.

Howard Ratner (Adam Sandler) is a once successful New York gems dealer whose gambling addiction has left his family and career in shambles, and him hundreds of thousands in debt. Always looking for the next big bet, Howard thinks he finally hit it big when he discovers a rare uncut rock of Ethiopian gems, with a very interested high-profile buyer. But the closer Howard gets to finally winning big, the more he is forced to realize he can't keep running from the consequences of his actions.