An artist on the verge of a career-changing exhibition navigates family, friends and colleagues in the lead-up to her show and finds that the chaos of life becomes the inspiration for more great art.

Over the summer, a series of unfortunate happening triggers a financial crisis for a young woman and she soon finds her life falling apart.

Settlers traveling through the Oregon desert in 1845 find themselves stranded in harsh conditions.

Cozy, a dissatisfied housewife, meets Lee at a bar. A drink turns into a home break-in, and a gun shot sends them on the run together, thinking they've committed murder.

Josh and Dena, two young environmental activists, are planning a large scale act to force the world to think about what they're doing to the environment. They pull in Harmon, a man with a sketchy past, to help them pull off their big plan. However, unforeseen consequences bring a whole host of guilt, paranoia and other problems, and their ultimate act will change themselves more than the world around them.

Two old friends, Kurt and Mark, reunite for a weekend camping trip in the Cascade mountain range east of Portland, Oregon. When they arrive at their final destination, a hot spring deep in the forest, they must confront the divergent paths they have taken in life.

Certain Women drops us into a handful of intersecting lives across Montana. A lawyer (Laura Dern) tries to defuse a hostage situation and calm her disgruntled client (Jared Harris), who feels slighted by a workers' compensation settlement. A married couple (Michelle Williams and James Le Gros) breaks ground on a new home but exposes marital fissures when they try to persuade an elderly man to sell his stockpile of sandstone. A ranch hand (Lily Gladstone) forms an attachment to a young lawyer (Kristen Stewart), who inadvertently finds herself teaching a twice-weekly adult education class, four hours from her home.

A loner and cook (John Magaro) has traveled west and joined a group of fur trappers in Oregon Territory, though he only finds connection with a Chinese immigrant (Orion Lee). The men collaborate on a business, although its longevity is reliant upon the participation of a wealthy landowner's prized milking cow.