Follows the journey of John and Colt, gunfighters and sometimes lovers, on parallel but very different journeys through an underground dueling culture.

Rodrigo, a piano-tuner and former composer fallen on hard times, begins a love affair with Susana. She is soon-to-be-married to his friend, Isaias. When a bomb in the city of Medellín nearly kills them, they surrender to their attraction and fall into each other's arms. Cocooned in her apartment above the vibrant city, she opens up to him every night and tells him a story of each of the different men from her past. Her stories inspire him to compose again, but his obsession makes him jealous and paranoid. When she finally leaves her fiancé to be with Rodrigo, he becomes obsessed with her fidelity.

A hotel room shootout between two assassins kicks off a long night of bodies falling like dominoes, as we follow a chain of crooked cops, gangsters, hitmen, a femme Fatale and an ex-mercenary through a confluence of murder, betrayal, revenge and redemption.