The story of the love affair between FDR and his distant cousin Margaret "Daisy" Suckley, centered around the weekend in 1939 when the King and Queen of the United Kingdom visited upstate New York.

A British couple return to Paris many years after their honeymoon there in an attempt to rejuvenate their marriage.

Francis and Blake Falls are conjoined twins who live in a neat little room in a rundown hotel. While sharing some organs, Blake is always fit and Francis is very sickly. Into their world comes a young lady, who turns their world upside down. She gets involved with Blake, and convinces the two to attend a Halloween party, where they can pass themselves off as wearing a costume. Eventually Francis becomes really ill, and they have to be separated. They then face the physical and mental strains that come from their proposed separation. Viewers will be inclined to believe that the two are really Siamese twins, but in fact they are simply real-life brothers playing the parts convincingly.

Toots and May's marriage is one of Toots being dependent on his wife. Shortly after Toots and May arrive in London to visit with their grown children Bobby and Paula and their respective children, Toots falls ill and dies. Toots' death brings to the surface the underlying strain that has always existed between May and both of her two children, and the unhappy lives they have all led. Now specifically with Paula, May is disapproving of her relationship with a construction worker named Darren. Not only does May think his occupation makes him beneath Paula, he's also a married man. Darren is in an unsatisfying marriage but doesn't want to leave it if only because of his son. Even after May gets to know and like Darren, she still encourages Paula to break up with him. The issue is that May herself has fallen in love with Darren, the two who begin a sexual relationship. What will ultimately happen between May and Darren also depends on Darren, who is floundering in his own life and doesn't really know what he wants or even if he did how to get it. What will happen may also depend on Paula if she finds out what's going on.

Philip, an orphan, was taken in and brought up by his cousin Ambrose, a Devon landowner he loves like a father. At a time, Ambrose, who has been advised by his physician a warmer climate, leaves for Tuscany. There he meets and marry Rachel, a half-Italian cousin of his. After an idyllic outset, the situation deteriorates. Shortly before his death, Ambrose manages to alert Philip: his wife is killing him slowly. Willing to sort out the truth, Philip goes to Ambrose's place but he does not find Rachel, who has gone away. Instead he meets Rainaldi, her friend and lawyer, who does not inspire him with confidence. He returns to his estate, persuaded that Rachel is evil and is the direct cause of Ambrose's death. Some time later, Rachel announces her coming. Determined to welcome her coolly, he is stunned to discover a woman not only beautiful but elegant, intelligent and sensitive. Instead of strangling her like he said he would, he falls in love. Madly.