Deep in the underbelly of New York City, a five year-old girl and her mother live among a community that has claimed the abandoned subway tunnels as their home.

Lee Chandler is a brooding, irritable loner who works as a handyman for a Boston apartment block. One damp winter day he gets a call summoning him to his hometown, north of the city. His brother's heart has given out suddenly, and he's been named guardian to his 16-year-old nephew. As if losing his only sibling and doubts about raising a teenager weren't enough, his return to the past re-opens an unspeakable tragedy.

Paul lives an isolated life with his father in upstate New York. He finds making friends impossible due to a rare condition he has known as congenital hypertrichosis - an affliction that causes an abnormal amount of hair growth all over his face and body. On his 13th birthday, Paul receives a mysterious gift that compels him to run away and seek out the mother he has never known.