Two years after the events in "Final Fantasy VII", a disease called 'Seikon-Shoukougun', or 'Geostigma', is spreading through the planet. This disease is believed to have been caused by the body fighting off foreign material that invaded the body two years earlier, at the end of "Final Fantasy VII". Guilt-ridden and haunted by his past, ex-SOLDIER Cloud Strife has decided to live a secluded, solitary life away from his friends while maintaining "Strife's Delivery Service", whose headquarters is located in Tifa Lockheart's bar, the Seventh Heaven. Tifa's bar serves as an orphanage for children stricken with Geostigma. Here, Tifa keeps an eye on Barret's six-year-old daughter, Marlene, while Barret searches the planet for an alternative energy source to the Planet's energy, Mako. One day, Cloud receives a phone call from the former Shinra, Inc. president, Rufus, asking him for protection from a mysterious man named Kadaj. Kadaj, in the meantime, along with his brothers Loz and Yazoo, are searching for their "mother", and seem to believe that Cloud knows where to find her. Meanwhile, Vincent Valentine has been wandering the planet gathering information on Kadaj's scheme, and Cloud and his friends must come together again to fight these new enemies.

Lara Croft (Alicia Vikander) is the fiercely independent daughter of eccentric adventurer Lord Richard Croft (Dominic West), who vanished when she was scarcely a teen. Now a young woman of twenty-one without any real focus or purpose, Lara navigates the chaotic streets of trendy East London as a bike courier, barely making the rent, and takes college courses, rarely making it to class. Determined to forge her own path, she refuses to take the reins of her father's global empire just as staunchly as she rejects the idea that he's truly gone. Advised to face the facts and move forward after seven years without him, even Lara can't understand what drives her to finally solve the puzzle of his mysterious death. Going explicitly against his final wishes, she leaves everything she knows behind in search of her dad's last-known destination: a fabled tomb on a mythical island that might be somewhere off the coast of Japan. But her mission will not be an easy one; just reaching the island will be extremely treacherous. Suddenly, the stakes couldn't be higher for Lara, who, against the odds and armed with only her sharp mind, blind faith, and inherently stubborn spirit, must learn to push herself beyond her limits as she journeys into the unknown. If she survives this perilous adventure, it could be the making of her, earning her the name "tomb raider".