A college freshman discovers a dark secret about the sorority house she's pledging for after a series of murders terrorize the campus.

Set in the glamour of 1950s post-war London, renowned dressmaker Reynolds Woodcock (Daniel Day-Lewis) and his sister Cyril (Lesley Manville) are at the center of British fashion, dressing royalty, movie stars, heiresses, socialites, debutants, and dames with the distinct style of The House of Woodcock. Women come and go through Woodcock's life, providing the confirmed bachelor with inspiration and companionship, until he comes across a young, strong-willed woman, Alma (Vicky Krieps), who soon becomes a fixture in his life as his muse and lover. Once controlled and planned, he finds his carefully tailored life disrupted by love.

An American writer arrives in London where he meets Nicola Six, a beautiful woman who soon becomes his muse. She is playing a dangerous game, dating a small-time (married) gangster and a wealthy businessman in an effort to con them both. A clairvoyant, she has premonitions of her own death, at the hands of one of the three men she is involved with.