It is the end of World War I and the young Italian soldiers are making their way back to San Giovanni Rotondo, a land of poverty, with a tradition of violence and submission to the iron-clad rule of the church and its wealthy landowners. Families are desperate, the men are broken, albeit victorious. Padre Pio also arrives, at a remote Capuchin monastery, to begin his ministry, evoking an aura of charisma, saintliness and epic visions of Jesus, Mary and the Devil himself. The eve of the first free elections in Italy sets the stage for a massacre with a metaphorical dimension: an apocalyptic event that changes the course of history.

Scheming to save their father's ranch, the Alvarez brothers find themselves in a war with Mexico's most feared drug lord.

Recently ordained a priest, 24-year-old Father Amaro is sent to a small parish church in Los Reyes, Mexico to assist the aging Father Benito in his daily work. Benito--for years a fixture in the church as well as the community--welcomes Father Amaro into a new life of unseen challenges. Upon arriving in Los Reyes, the ambitious Father Amaro meets Amelia, a beautiful 16-year-old girl whose religious devotion soon becomes helplessly entangles in a growing attraction to the new priest. Amelia is quickly following into the footsteps of her mother, Sanjuanera, who has been engaged in a long-time affair with Father Benito. Amaro soon discovers that corruption and the Church are old acquaintances in Los Reyes. Father Benito has been receiving financial help from the region's drug lord for the construction of a new health clinic. As well, another priest in the diocese, Father Natalio, is suspected of assisting guerilla troops in the highlands. Maenwhile, Amelia and Father Amaro have fallen in love and have begun a passionate sexual relationship. As things become increasingly more complicated in the small community, the walls around Father Amaro begin to crumble. Torn between the divine and the carnal, the righteous and the unjust, Father Amaro must summon his strength to choose which life he will lead.

It tells the story of the Padre (Roth), a small-time con man on the run from his dogged pursuers, U.S. Court Justice Nemes (Nolte) and local police officer Gaspar (Guzmán). When the Padre is caught mid-con, he flees the scene in a stolen car, unaware that a precocious 16-year-old girl, Lena (Henriquez), is stowing away in the back seat. After she blackmails him into letting her join his journey, the duo plan their biggest heist yet - not always aware of the dangers of working with each other and the law closing in on them.